The pkgsrc packages ghostscript6 and ghostscript-esp are probably going to be removed. Do `pkg_info | grep ghostscript` to see if this affects you.
Any readers involved with Python source? There’s two extant Python patches that Hasso Tepper put together for Python 2.5 and 2.4, languishing.
On a more positive note, an upstream fix for Perl was added promptly.